Assessing a Variant of Uncertain Significance (VUS) If you have a received a VUS from clinical genetic testing and would like to understand its importance for your patient, this guide may be helpful for you.

The laboratory uses computer programs and genetic databases to help figure out if a variant will change how a gene works. But sometimes, there just isn’t enough information to know for sure.

Variant Score model: The Variant Score model is a partially pooled, hierarchical Bayesian inference model for interpreting genetic variants across multiple genes.

Recessive: Variant that reduces gene function, but that only causes a biochemical abnormality - or disease - if in trans to a LoF allele.

May 17, 2021 · Genetic variants of SARS-CoV-2 have been emerging and circulating around the world throughout the COVID-19 pandemic. Viral mutations and variants in the United States are routinely …

When you agreed to have gene testing for gene mutations, you probably were expecting a “yes” or “no” answer. But the result of gene testing is not always a clean “yes” or “no”. In your case, the test came …

oring: XFG Executive Summary XFG has been designated a SARS-CoV-2 variant under monitoring (VUM) with increasing proportion. globally. Considering the available evidence, the additional public …