In chemical analysis, matrix refers to the components of a sample other than the analyte [1] of interest. The matrix can have a considerable effect on the way the analysis is conducted and the quality of the …

Oct 19, 2023 · Matrix effect refers to the loss of analyte signal due to the presence of a matrix such as food, urine, plasma or blood. This signal loss can be quantified by comparing it to the signal of the …

A process called standard addition can often be used to assess whether a sample has a matrix effect. If the sample does have a matrix effect, the standard addition procedure will provide a more accurate …

Matrix effects refer to the significant influence of material properties, such as particle size, component location, density, and porosity, on optical spectroscopy results, particularly in solid turbid samples.

A matrix effect describes the changes observed in the detection or quantification of an analyte when other substances are present in the sample. The implications of this phenomenon are manifold.

The intensity of secondary ions depends not only on the concentration of the element, but also on the type and composition of the material (matrix). This is called the “SIMS matrix effect”. For primary ion …

This review aims to highlight common challenges associated with matrix effects throughout the entire analytical process with emphasis on gas chromatography-mass spectrometry, liquid chromatography …

What is the Matrix Effect? The combined effect on signal response of all components of the sample, other than the analyte itself, is called the matrix effect.

Sep 22, 2025 · Learn why matrix effects cause recovery results to be offset with real examples and when to correct them using blank-matrix based calibration curves.

Mar 10, 2025 · Matrix effects in LC can enhance or suppress detector responses, impacting quantitation accuracy. Understanding these effects is crucial for method development and troubleshooting.