Did you know: Your brain is constantly renewing itself through a process known as phagocytosis, in which cells surround and break down smaller cells or molecules.
A microglia replacement approach demonstrates that brain macrophages with patient mutations from Aicardi–Goutières syndrome, a genetic, brain predominant interferonopathy, are sufficient to drive ...
Blocking microglia prevents infant forgetting and improves memory in mice, suggesting they play a key role in memory ...
A Dartmouth study published in Nature Communications reveals that immune cells in the brain use a surprising two-step process ...
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Ageing slows brain protein clearance and shifts synaptic waste to microglia
By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...
By analyzing tissue from patients with Parkinson's disease, and animal and cellular models of the disease, a research team ...
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Aging brains struggle to recycle synaptic proteins
As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why. It is increasingly clear, though, that the loss of synapses-the flexible and adaptive relay ...
Researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study also integrates drug databases with real ...
“By the time we examine an autopsied brain-tissue sample, a pathologist will have rinsed it with alcohol, removing lipids,” said Tony Wyss-Coray, PhD, the D. H. Chen Professor II, a professor of ...
Astrocyte-microglia communication: influences of aging, sex, and health states in network physiology
The field of network physiology is increasingly focused on understanding how complex cell interactions within the central ...
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