Background: Whether the enteric absorption of the neuraminidase inhibitor oseltamivir is impaired in critically ill patients is unknown. We documented the pharmacokinetic profile of oseltamivir in ...

Drugs are used to prevent, alleviate and treat a variety of illnesses, ranging from the common flu to acute infection to chronic diseases like arthritis. Although the expenditure for drug development ...

Though studies evaluating the effects of posture on the absorption of drugs have been conducted, a systematized review revealed critical gaps in methodology. Of 18 original research articles selected ...

Chondroitin sulfate is a heterogeneous polysaccharide in terms of structure, molecular mass, and biological and pharmacological properties. The structure and properties of polysaccharides strongly ...

Phase I trial of laromustine in combination with infusional ara-C in elderly patients over age 60 with newly diagnosed AML or high-grade MDS ...

A comprehensive overview of pharmacokinetics principles can be found in Chapter 5 of the widely used therapeutics textbook Pharmacotherapy: A Pathophysiologic Approach, 6th edition. [1] In addition, ...