Pediatric acute myeloid leukemia (AML) is one of the most common acute leukemias in children. While treatment outcomes have improved in recent years ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

The immune system's gradual decline with age, known as immune aging, increases susceptibility to infections, autoimmune diseases, and cancers. T cells, crucial for adaptive immunity, undergo ...

The human genome is just over 6 feet 8 inches long, which is 2 inches taller than the average NBA basketball player and in total, a lot of nucleotides! But what if the amount of sequence diversity ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays ...

What we do know is that there are a lot of brain-specific alternative splicing events that consistently go wrong in neurological diseases. These include neurodevelopmental disorders, like autism ...

Researchers in the Landau lab, led by Dr. Dan Landau, hematology and medical oncology, recently developed a new technique to investigate how mutations in RNA splicing can lead to clonal hematopoiesis ...

Take a genomic eukaryotic sequence, match it with a mature eukaryotic mRNA or a reverse-translated protein sequence, and you’ll discover the location of introns. These, of course, are spliced out ...

Researchers have identified 813 possible cancer driver genes, significantly expanding the list of potential therapeutic targets for treating the disease. The genes help cancer cells grow through a non ...