In Fragile X syndrome, sensory signals from the outside world are integrated differently, causing them to be underrepresented by cortical pyramidal neurons in the brain, according to a new study. In ...

New research reveals how a class of neurons that help coordinate communication in the brain link up with their target cells, ...

Researchers in Japan built a miniature human brain circuit using fused stem-cell–derived organoids, allowing them to watch the thalamus and cortex interact in real time. They found that the thalamus ...

The human brain's advanced cognitive capabilities are often attributed to our recently evolved neocortex. Comparison of human and rodent brains shows that the human cortex is thicker, contains more ...

In Fragile X syndrome (FXS), the most common cause of autism, sensory signals from the outside world are integrated differently, causing them to be underrepresented by cortical pyramidal neurons in ...

Using a new approach for studying live embryonic mouse brains at single-cell resolution, researchers headed by a team at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) have ...

Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...

Microglia respond to proteinopathies by changing their shapes and expression profiles in different ways. Here’s one that has been somewhat overlooked: rod-shaped microglia. These long, straight cells ...

Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechanisms are the subject of ongoing research and debate. When it comes to Huntington's disease, ...

New research from the Netherlands Institute for Neuroscience shows that chandelier cells, a specific type of brain cell, become active during unexpected situations. “Researchers have been wondering ...